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Biomed Comm
QSC-14 Optimal Health Trio


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A combination of three growth factors: IGF-1, PDGF, and TGF 1.

In the body these three growth factors protect against toxic damage to cells, repair damage, increase uptake of nutrients and minerals. The growth factors in this formula are crucial to cell survival and repair and have potent regenerative effects. Alcohol Free.

IGF1 (Insulin-like Growth Factor-1)

Insulin-like Growth Factor-1 (IGF1) is released by many different tissues throughout the body and affects almost every cell to some degree. Major organs that synthesize IGF1 are the human placenta, heart, lung, kidney, liver, pancreas, spleen, small intestines, testes, ovaries, large intestines, brain, bone and pituitary. Humans produce approximately 10 milligrams of IGF1 per day until about 30 years old whereby production decreases with aging. IGF1 has similarities to insulin and possesses potent anabolic and cell growth effects. IGF1 is also important for its affect on development, diabetes and other chronic diseases.

  • IGF1 is primarily secreted by the liver in response to a signal from human growth hormone (hGH). The major target tissues affected by the IGF1 in combination with the hGH signal are muscle, cartilage, bone, liver, kidney, nerves, skin and lungs.
  • IGF1 is known as a 'progression' factor. IGF1 assists competent cells toward cell division and often that is all cells need for successful activation. IGF1 cooperates with PDGF to increase the cell's ability to complete DNA synthesis. IGF1 not only helps cell growth by division, but also by enhancing cell specialization. Hormonal functions such as the anabolic (constructive) activity of hGH depends on the production and presence of IGF1 to achieve positive results.
  • IGF1 increases physical performance, mental performance, and physical endurance in healthy individuals.
  • IGF1 communicates an anabolic signal to cells, regulating cell division and differentiation as the muscle acquires an increased need for strength or as injury to the muscle is incurred.
  • IGF1 promotes the growth of muscle and bone.
  • IGF1 acts within the nervous system and is critical for the growth and development of nerve cells.
  • IGF1 maintains a high level of cell communication at the neuromuscular junction, where the cooperation between the nerve and muscle cells take place.

Studies show that after a one week period of strenuous exercise, blood levels of IGF1 are significantly increased due to either regenerative processes from muscle injury or higher requirements in muscles to handle the weight load.
In aging cells, there is a greater need for more IGF1 in order to move cells out of the 'resting phase' and into a growth phase of the cell cycle. A slower growth of cells during the aging process correlates with a higher requirement of IGF1 than the body supplies. The increase in cellular communication from an addition of IGF1 may bring the aging, slower cells back into the balanced state optimizing cell activity and tissue/organ performance.

Homeopathic IGF1

Homeopathic IGF1 works in many different areas of the body to facilitate and improve cellular performance. A recent independent double-blind, placebo-controlled clinical testing of homeopathic IGF1 demonstrated effectiveness in the nervous, reproductive, musculo/skeletal, and gastrointestinal systems. Specifically, homeopathic IGF1 improved energy levels and physical performance, respiratory conditions, and relieved symptoms of PMS and menopause. It also relieved muscle and bone aches and pains, joint stiffness, inflammation in the body, improved mental concentration and clarity and positively affected appetite. Increases in lean body mass also have been anecdotally reported. Homeopathic IGF1 balances weight by helping the body to achieve its ideal weight, whether that means losing weight for people too heavy, or gaining weight for people too lean.

IGF1 is believed to bring aging, resting cells back into a balanced state optimizing cell activity and tissue performance.

PDGF (Platelet-derived Growth Factor)

As we age or if we have a chronic illness increasing numbers of cells are in the resting state and have difficulty entering into an active state capable of repair. PDGF acts on resting cells to make them competent to enter the cell cycle.

Pain in the body indicates there is a wound which requires cell repair and cell regeneration. When blood clots as a result of a wound in the vascular system, the surrounding cells release various substances to facilitate the clotting and regenerative process. PDGF is one of the small proteins released. This growth factor allows unspecialized connective tissue cells, called fibroblasts, to divide and stimulate connective tissue cells and smooth muscle cells to divide at the wound site in order to repair the damaged area.

Platelets, macrophages, endothelial and smooth muscle cells from an injured area all secrete PDGF to assist in reparation, which in turn eases the pain associated with the wound. During wound healing two processes occur; first, PDGF stimulates the proliferation of fibroblasts and smooth muscle cells and second, macrophages and fibroblasts within the injured area produce more extra-cellular matrix material to close the wound.

Cells most responsive to PDGF are skin, vasculature, nervous system, immune system, smooth muscle cells (which control digestion, breathing and blood flow) and embryonic cells. As competence and progression factors, PDGF and IGF1, respectively work together to effectively move cells through the cell cycle.

TGFb1 (Transforming Growth Factor-1)

TGFb1 acts primarily as an on/off switch for cell multiplication and differentiation. TGFb1 regulates the receptors for IGF1 and PDGFBB. Individual cells behave differently in terms of cell division based on the cell type, the other proteins present and the concentration of TGFb1. Some cells up-regulate and some down-regulate DNA synthesis and/or cell division in the presence of TGF b1. Its effect on the cell depends on the status of the cell. TGFb1 helps epithelial cells (cells lining inner and outer surfaces) to specialize. When the cell is relatively unspecialized, like in tumor growth, the cell may experience an inhibitory effect, whereas if the cell is carrying out a specific role, this growth factor enhances cell activity. During inflammatory processes, TGF b1 orchestrates the healing process.

Cell proliferation activated by other growth factors or biologic effects of hormones is mediated by TGFb1. TGFb1 plays an important role in the cell division and differentiation in the areas of bone development and repair, cartilage growth and repair, blood cell development, fat cell development, and muscle cell specialization. It also is necessary for skin cell formation, and immune Tlymphocyte cell division. Thus tissue repair, immune function and regulation of inflammatory conditions all require TGF b1.

Homeopathic TGF b1

Also important in the wound healing processes, homeopathic TGF b1 assists in the relief of minor skin irritations and inflammation. Homeopathic TGFb1's anti-inflammatory properties work not only in the muscles and soft tissue, but also in the nervous system for relief of anxiety and the respiratory system for allergy relief. Similar to its function in the body, homeopathic TGFb1 may work in conjunction with homeopathic IGF1and homeopathic PDGFBB to maintain optimal cellular activity. Anecdotal evidence has shown the combination of homeopathic TGFb1, and homeopathic IGF1 to help alleviate fatigue.


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Homeopathic Educational Services logoDANA ULLMAN, MPH, is one of America's leading advocates for homeopathy. He has authored 10 books, including The Homeopathic Revolution: Why Famous People and Cultural Heroes Choose Homeopathy, Homeopathy A-Z, Homeopathic Medicines for Children and Infants, Discovering Homeopathy, and (the best-selling) Everybody's Guide to Homeopathic Medicines (with Stephen Cummings, MD). He is the founder of Homeopathic Educational Services, America's leading resource center for homeopathic books, tapes, medicines, software, and correspondence courses. Homeopathic Educational Services has co-published over 35 books on homeopathy with North Atlantic Books. Dana writes a regular column for the wildly popular website, www.Huffingtonpost.com (to access these articles, click HERE!).

 

STATEMENT ABOUT DANA ULLMAN, MPH, by DAVID ANICK, MD, PhD., Harvard School of Medicine: 

"You are the Jon Stewart of homeopathy, the way you combine information ("gee I didn't know that!") with humor.  And you avoid defensiveness, which is terrific."

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